Add to ORKGIntroduction: The heart is one of the least regenerative organs in the body and any major insult can result in a significant loss of heart cells. The development of an in vitro-based cardiac tissue could be of paramount importance for many aspects of the cardiology research. In this context, we developed an in vitro assay based on human cardiomyocytes (hCMs) and ad hoc micro-technologies, suitable for several applications: from pharmacological analysis to physio-phatological studies on transplantable hCMs. We focused on the development of an assay able to analyze not only hCMs viability, but also thei
The emerging heart-on-a-chip platforms are promising approaches to establish cardiac cell/tissue mod...
Contractility of the myocardium engines the pumping function of the heart and is enabled by the coll...
Cardiomyocytes derived from human pluripotent stem cells (hPSC-CMs) hold a great potential as human ...
INTRODUCTION: The heart is one of the least regenerative organs in the body and any major insult can...
<div><h3>Introduction</h3><p>The heart is one of the least regenerative organs in the body and any m...
micro-technologies, suitable for several applications: from pharmacological analysis to physio-phat...
Development of new drugs is of high interest for the field of cardiac and cardiovascular diseases, w...
Abstract The capacity of pluripotent stem cells both for self-renewal and to differentiate into an...
The capacity of pluripotent stem cells both for self-renewal and to differentiate into any cell type...
The study of human cardiomyopathies and the development and testing of new therapies has long been l...
More relevant and reliable preclinical cardiotoxicity tests are required to improve drug safety and ...
Objectives: Human embryonic stem cell-derived cardiomyocytes (hESC-CM) are investigated as a source ...
Heart failure due to hypertension, infarction, or other factors, is a leading killer of men and wome...
Abstract—Cell replacement therapy is a promising approach for the treatment of cardiac diseases, but...
<p>The overall increase in cardiovascular diseases and, specifically, the ever-rising exposure...
The emerging heart-on-a-chip platforms are promising approaches to establish cardiac cell/tissue mod...
Contractility of the myocardium engines the pumping function of the heart and is enabled by the coll...
Cardiomyocytes derived from human pluripotent stem cells (hPSC-CMs) hold a great potential as human ...
INTRODUCTION: The heart is one of the least regenerative organs in the body and any major insult can...
<div><h3>Introduction</h3><p>The heart is one of the least regenerative organs in the body and any m...
micro-technologies, suitable for several applications: from pharmacological analysis to physio-phat...
Development of new drugs is of high interest for the field of cardiac and cardiovascular diseases, w...
Abstract The capacity of pluripotent stem cells both for self-renewal and to differentiate into an...
The capacity of pluripotent stem cells both for self-renewal and to differentiate into any cell type...
The study of human cardiomyopathies and the development and testing of new therapies has long been l...
More relevant and reliable preclinical cardiotoxicity tests are required to improve drug safety and ...
Objectives: Human embryonic stem cell-derived cardiomyocytes (hESC-CM) are investigated as a source ...
Heart failure due to hypertension, infarction, or other factors, is a leading killer of men and wome...
Abstract—Cell replacement therapy is a promising approach for the treatment of cardiac diseases, but...
<p>The overall increase in cardiovascular diseases and, specifically, the ever-rising exposure...
The emerging heart-on-a-chip platforms are promising approaches to establish cardiac cell/tissue mod...
Contractility of the myocardium engines the pumping function of the heart and is enabled by the coll...
Cardiomyocytes derived from human pluripotent stem cells (hPSC-CMs) hold a great potential as human ...