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stem cellAnatomical structure
The stem cell theory of aging postulates that aging is the result of the failure of tissue specific stem cells to replenish tissues and to sustain tissue function. Stem cell functions decline with age, consistent with the degeneration and dysfunction of aging regenerative tissues. Stem cell dysfunction is associated with premature aging and evidence is emerging to suggest that stem cell manipulation can extend lifespan [1]. Longevity factors tend to be enriched or activated in stem cells compared to their differentiated progeny and are essential for stem cell maintenance [2, 3], providing further support to the stem cell theory of aging. Adult stem cells are maintained in a metabolically inactive quiescent state for prolonged periods of tim...
Stem cells hold great promise for regenerative therapies for a wide spectrum of diseases and disorde...
Aging is by far the dominant risk factor for the development of cardiovascular diseases, whose preva...
Aging is by far the dominant risk factor for the development of cardiovascular diseases, whose preva...
Stem cells are defined by their extensive self-renewal properties, and yet there is abundant evidenc...
Stem cells are defined by their extensive self-renewal properties, and yet there is abundant evidenc...
Stem cells are defined by their extensive self-renewal properties, and yet there is abundant evidenc...
Stem cells are defined by their extensive self-renewal properties, and yet there is abundant evidenc...
Stem cells are defined by their extensive self-renewal properties, and yet there is abundant evidenc...
BACKGROUND: Aging tissues lose their homeostatic and regenerative capacities, which has been linked ...
Emerging evidence indicates that epigenetic regulators are critically required for the maintenance o...
Adult stem cells have become the focus of intense research in recent years as a result of their role...
BACKGROUND: Recent evidence suggested that we grow old partly because of our stem cells grow old as ...
Mammalian aging is associated with reduced tissue regeneration, increased degenerative disease, and ...
Mammalian aging is associated with reduced tissue regeneration, increased degenerative disease, and ...
BACKGROUND: There is probably no single way to age. Indeed, so far there is no single accepted expla...
Stem cells hold great promise for regenerative therapies for a wide spectrum of diseases and disorde...
Aging is by far the dominant risk factor for the development of cardiovascular diseases, whose preva...
Aging is by far the dominant risk factor for the development of cardiovascular diseases, whose preva...
Stem cells are defined by their extensive self-renewal properties, and yet there is abundant evidenc...
Stem cells are defined by their extensive self-renewal properties, and yet there is abundant evidenc...
Stem cells are defined by their extensive self-renewal properties, and yet there is abundant evidenc...
Stem cells are defined by their extensive self-renewal properties, and yet there is abundant evidenc...
Stem cells are defined by their extensive self-renewal properties, and yet there is abundant evidenc...
BACKGROUND: Aging tissues lose their homeostatic and regenerative capacities, which has been linked ...
Emerging evidence indicates that epigenetic regulators are critically required for the maintenance o...
Adult stem cells have become the focus of intense research in recent years as a result of their role...
BACKGROUND: Recent evidence suggested that we grow old partly because of our stem cells grow old as ...
Mammalian aging is associated with reduced tissue regeneration, increased degenerative disease, and ...
Mammalian aging is associated with reduced tissue regeneration, increased degenerative disease, and ...
BACKGROUND: There is probably no single way to age. Indeed, so far there is no single accepted expla...
Stem cells hold great promise for regenerative therapies for a wide spectrum of diseases and disorde...
Aging is by far the dominant risk factor for the development of cardiovascular diseases, whose preva...
Aging is by far the dominant risk factor for the development of cardiovascular diseases, whose preva...
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