Background: Cancer is one of the highly virulent diseases known to humankind with a high mortality rate. Breast cancer is the most common cancer in women worldwide. Sorghum is a principal cereal food in many parts of the world, and is critical in folk medicine of Asia and Africa. In the present study, we analyzed the effects of HSE in metastatic breast cancer. Methodology/Principal Findings: Preliminary studies conducted on MDA-MB 231 and MCF-7 xenograft models showed tumor growth suppression by HSE. Western blotting studies conducted both in vivo and in vitro to check the effect of HSE in Jak/STAT pathways. Anti-metastatic effects of HSE were confirmed using both MDA-MB 231 and MCF-7 metastatic animal models. These studies showed that HSE ...
Aberrantly activated signal transducer and activator of transcription (STAT) proteins are implicated...
Overexpression of human epidermal growth factor receptor 2 (HER2) drives the biology of 30% of breas...
Epidemiological evidence has correlated consumption of sorghum with reduced incidences of gastrointe...
BACKGROUND: Cancer is one of the highly virulent diseases known to humankind with a high mortality r...
<div><p>Background</p><p>Cancer is one of the highly virulent diseases known to humankind with a hig...
Cancer is one of the highly virulent diseases known to humankind with a high mortality rate. Breast ...
Colon cancer (CC) is considered a high-risk cancer in developed countries. Its etiology is correlate...
<p>A, breast cancer cells MDA-MB 231, MCF-7, and SKBR-3 were treated with HSE. After 24 h, cell viab...
Triple-negative breast cancer (TNBC) is characterized by the absence of estrogen receptor-α progeste...
Copyright © 2015 Xiang-Yan Chen et al. This is an open access article distributed under the Creative...
Ultraviolet irradiation-induced hyperpigmentation of the skin is associated with excessive melanin p...
Black cohosh is an herbal supplement used by women to control the symptoms of menopause, mainly hot ...
Cancer metastasis is refractory to most forms of chemotherapy. Conventional and alternative drugs, s...
Introduction: It was suggested that specific plants may reduce cancer's resistance to chemotherapy. ...
Cancer inflammation promotes cancer progression, resulting in a high risk of cancer. Here, we demons...
Aberrantly activated signal transducer and activator of transcription (STAT) proteins are implicated...
Overexpression of human epidermal growth factor receptor 2 (HER2) drives the biology of 30% of breas...
Epidemiological evidence has correlated consumption of sorghum with reduced incidences of gastrointe...
BACKGROUND: Cancer is one of the highly virulent diseases known to humankind with a high mortality r...
<div><p>Background</p><p>Cancer is one of the highly virulent diseases known to humankind with a hig...
Cancer is one of the highly virulent diseases known to humankind with a high mortality rate. Breast ...
Colon cancer (CC) is considered a high-risk cancer in developed countries. Its etiology is correlate...
<p>A, breast cancer cells MDA-MB 231, MCF-7, and SKBR-3 were treated with HSE. After 24 h, cell viab...
Triple-negative breast cancer (TNBC) is characterized by the absence of estrogen receptor-α progeste...
Copyright © 2015 Xiang-Yan Chen et al. This is an open access article distributed under the Creative...
Ultraviolet irradiation-induced hyperpigmentation of the skin is associated with excessive melanin p...
Black cohosh is an herbal supplement used by women to control the symptoms of menopause, mainly hot ...
Cancer metastasis is refractory to most forms of chemotherapy. Conventional and alternative drugs, s...
Introduction: It was suggested that specific plants may reduce cancer's resistance to chemotherapy. ...
Cancer inflammation promotes cancer progression, resulting in a high risk of cancer. Here, we demons...
Aberrantly activated signal transducer and activator of transcription (STAT) proteins are implicated...
Overexpression of human epidermal growth factor receptor 2 (HER2) drives the biology of 30% of breas...
Epidemiological evidence has correlated consumption of sorghum with reduced incidences of gastrointe...