A single nucleotide polymorphism in the ZNF804A gene, rs1344706, is associated with schizophrenia. The polymorphism has been suggested to alter fetal expression of ZNF804A. It has also been reported to be associated with altered cortical functioning and neural connectivity in the brain. Since developmental mechanisms are suggested in the pathophysiology for schizophrenia, expression of Zfp804A, the rat homolog of ZNF804A, was investigated in the developing rat brain. We found that expression of Zfp804A in most brain regions is developmentally regulated and peaks around birth, where after it decreases towards adult levels. This time point is developmentally the equivalent to the second trimes-ter of fetal development in humans. An exception ...
Background Variation in the gene encoding zinc finger binding protein 804A (ZNF804A) is associated w...
<b><i>Background:</i></b> The rs1344706 single nucleotide polymorphism in the <i>ZNF804A</i> gene is...
A trio of genome-wide association studies recently reported sequence variants at three loci to be si...
OBJECTIVE: The single-nucleotide polymorphism rs1344706, located within an intron of the ZNF804A ge...
Objective. The single-nucleotide polymorphism rs1344706, located within an intron of the ZNF804A ge...
The zinc finger protein ZNF804A rs1344706 variant is a replicated genome-wide significant risk varia...
ZNF804A was (at the time this work started) one of only a few robustly implicated schizophrenia susc...
IMPORTANCE: The single-nucleotide polymorphism rs1344706 in the zinc finger protein 804A gene (ZNF80...
Context: Studies have shown patterns of abnormal dorsolateral prefrontal cortex (DLPFC) functional c...
To access publisher full text version of this article. Please click on the hyperlink in Additional L...
grantor: University of TorontoSchizophrenia is a disabling mental illness characterized by...
Context: The Zinc Finger Protein 804A gene (ZNF804A) has been implicated in schizophrenia susceptibi...
Genome-wide association studies have convincingly implicated several novel genes in susceptibility t...
Antagonists of the N-methyl-D-aspartate (NMDA)-type glutamate receptor induce psychosis in healthy i...
Antagonists of the N-methyl-D-aspartate (NMDA)-type glutamate receptor induce psychosis in healthy i...
Background Variation in the gene encoding zinc finger binding protein 804A (ZNF804A) is associated w...
<b><i>Background:</i></b> The rs1344706 single nucleotide polymorphism in the <i>ZNF804A</i> gene is...
A trio of genome-wide association studies recently reported sequence variants at three loci to be si...
OBJECTIVE: The single-nucleotide polymorphism rs1344706, located within an intron of the ZNF804A ge...
Objective. The single-nucleotide polymorphism rs1344706, located within an intron of the ZNF804A ge...
The zinc finger protein ZNF804A rs1344706 variant is a replicated genome-wide significant risk varia...
ZNF804A was (at the time this work started) one of only a few robustly implicated schizophrenia susc...
IMPORTANCE: The single-nucleotide polymorphism rs1344706 in the zinc finger protein 804A gene (ZNF80...
Context: Studies have shown patterns of abnormal dorsolateral prefrontal cortex (DLPFC) functional c...
To access publisher full text version of this article. Please click on the hyperlink in Additional L...
grantor: University of TorontoSchizophrenia is a disabling mental illness characterized by...
Context: The Zinc Finger Protein 804A gene (ZNF804A) has been implicated in schizophrenia susceptibi...
Genome-wide association studies have convincingly implicated several novel genes in susceptibility t...
Antagonists of the N-methyl-D-aspartate (NMDA)-type glutamate receptor induce psychosis in healthy i...
Antagonists of the N-methyl-D-aspartate (NMDA)-type glutamate receptor induce psychosis in healthy i...
Background Variation in the gene encoding zinc finger binding protein 804A (ZNF804A) is associated w...
<b><i>Background:</i></b> The rs1344706 single nucleotide polymorphism in the <i>ZNF804A</i> gene is...
A trio of genome-wide association studies recently reported sequence variants at three loci to be si...