Spaceflight is associated with deregulation in the immune system. Head-down bed rest (HDBR) at-6 ° is believed to be the most practical model for examining multi-system responses to microgravity in humans during spaceflight. In the present study, a 45-day HDBR was performed to investigate the alterations in human immune cell distributions and their functions in response to various stimuli. The effect of countermeasure, Rhodiola rosea (RR) treatment, was also examined. A significant decrease of interferon-γ (IFN-γ) and interleukin-17 (IL-17) productions by activated T cells, increase of IL-1β and IL-18 by activated B and myeloid cells were observed during HDBR. The upregulation of serum cortisol was correlated with the changes of IL-1 family...
Determining the effect of space travel on the human immune system has proven to be extremely challen...
There is ample evidence to suggest that space flight leads to immune system dysregulation. This may ...
Immune dysfunction is encountered during spaceflight. Various aspects of spaceflight, including micr...
Spaceflight is associated with deregulation in the immune system. Head-down bed rest (HDBR) at -6° i...
Spaceflight is associated with deregulation in the immune system. Head-down bed rest (HDBR) at -6 de...
Evidence from both human and rodent studies has indicated that alterations in immunological paramete...
In spaceflight, astronauts will be exposed to several environmental risk factors that may lead to di...
The immune system belongs to the most affected systems during spaceflight, and sensitivity of cells ...
As logistical access for in-flight space research becomes more limited, the use of ground based spac...
The immune system belongs to the most affected systems during spaceflight, and sensitivity of cells ...
peer reviewedOpportunities for microbes to establish infections are enhanced under spaceflight condi...
Long-duration spaceflight is known to cause immune dysregulation in astronauts. Biomarkers of immune...
Alterations in immune function have been documented during or post-spaceflight and in ground based m...
Space flight exerts a specific conglomerate of stressors on humans that can modulate the immune syst...
The health risks of a dysregulated immune response during spaceflight are important to understand as...
Determining the effect of space travel on the human immune system has proven to be extremely challen...
There is ample evidence to suggest that space flight leads to immune system dysregulation. This may ...
Immune dysfunction is encountered during spaceflight. Various aspects of spaceflight, including micr...
Spaceflight is associated with deregulation in the immune system. Head-down bed rest (HDBR) at -6° i...
Spaceflight is associated with deregulation in the immune system. Head-down bed rest (HDBR) at -6 de...
Evidence from both human and rodent studies has indicated that alterations in immunological paramete...
In spaceflight, astronauts will be exposed to several environmental risk factors that may lead to di...
The immune system belongs to the most affected systems during spaceflight, and sensitivity of cells ...
As logistical access for in-flight space research becomes more limited, the use of ground based spac...
The immune system belongs to the most affected systems during spaceflight, and sensitivity of cells ...
peer reviewedOpportunities for microbes to establish infections are enhanced under spaceflight condi...
Long-duration spaceflight is known to cause immune dysregulation in astronauts. Biomarkers of immune...
Alterations in immune function have been documented during or post-spaceflight and in ground based m...
Space flight exerts a specific conglomerate of stressors on humans that can modulate the immune syst...
The health risks of a dysregulated immune response during spaceflight are important to understand as...
Determining the effect of space travel on the human immune system has proven to be extremely challen...
There is ample evidence to suggest that space flight leads to immune system dysregulation. This may ...
Immune dysfunction is encountered during spaceflight. Various aspects of spaceflight, including micr...