Spatial models for point and areal data using Markov random fields on a fine grid

I consider the use of Markov random fields (MRFs) on a fine grid to represent latent spatial processes when modeling point-level and areal data, including situations with spatial mis-alignment. Point observations are related to the grid cell in which they reside, while areal observations are related to the (approximate) integral over the latent process within the area of interest. I review several approaches to specifying the neighborhood structure for constructing the MRF precision matrix, presenting results comparing these MRF representations analyti-cally, in simulations, and in two examples. The results provide practical guidance for choosing a spatial process representation and highlight the importance of this choice. In particular, the results demonstrate that, and explain why, standard CAR models can behave strangely for point-level data. They show that various neighborhood weighting approaches based on higher-order neighbors that have been suggested for MRF models do not produce smooth fields, which raises doubts about their utility. Finally, they indicate that an MRF that approximates a thin plate spline compares favorably to standard CAR models and to kriging under many circum-stances.