The equatorial current sheet in pulsar magnetospheres is often regarded as an ideal site for particle acceleration via relativistic reconnection. Using 2D spherical particle-in-cell simulations, we investigate particle acceleration in the axisymmetric pulsar magnetosphere as a function of the injected plasma multiplicity and magnetization. We observe a clear transition from a highly charge-separated magnetosphere for low plasma injection with little current and spin-down power, to a nearly force-free solution for high plasma multiplicity characterized by a prominent equatorial current sheet and high spin-down power. We find significant magnetic dissipation close to the Y-point, up to about 30 % in the high-multiplicity regime. Additional di...