We consider a reach-avoid differential game, in which one of the players aims to steer the system into a target set with-out violating a set of state constraints, while the other player tries to prevent the first from succeeding; the system dynam-ics, target set, and state constraints may all be time-varying. The analysis of this problem plays an important role in colli-sion avoidance, motion planning and aircraft control, among other applications. Previous methods for computing the guaranteed winning initial conditions and strategies for each player have either required augmenting the state vector to include time, or have been limited to problems with either no state constraints or entirely static targets, constraints and dynamics. To inco...