THE THERAPEUTIC EFFECTIVENESS OF HONEY IN ORAL

Th e aim of this study was to describe and quantify the therapeutic value of honey in oral mucosal ulcers healing in comparison with Glyceroloxytriester (TGO). We also aimed to biochemically evaluate the healing eff ects of honey which had been collected from the Blacksea region fl ora on mucosal ulcers resulting in material loss. Th irty wistar rats (± g) were enrolled in this study. Excisional wounds were per-formed in all rats for animal oral mucosal ulcer model. Th ey were randomly allocated to three groups: group was treated with Apitherapeutic agent or honey (, ml, x), group was treated with TGO (,ml, x) locally, Group served as the control group. Following the surgical procedure on day , biopsy specimens were taken from right buc-cal mucosa and on day biopsy specimens were taken from left bucal mucosa in all rats. Afterwards, hydroxy pyroline levels were measured. Data were analyzed statistically. Th ere was no statistically signifi cant diff erence between Group and , and also between Group and , but there was statistically signifi cant diff erence between Group and on day . Th ere was no statistically signifi cant diff erence between Group , and on day