Analysis of pathohistological

Pterygium internum (external eye layer) shows great recurrence tendency after surgical removal. Its etiology is still unclear and represents a signifi cant problem. Th e main goal of our study was to explore the interrelationships of pathohistological characteristics of pterygium, namely presence of infl ammation, vascularisation degree and fi brinoid changes and on the basis of their analysis to test the possibility of predicting its evolution and recurrence. Th e analysis was performed on the material taken from patients surgically treated by the technique of Arlt. Th e specimens were stained using the classical histochemical methods: hematoxylin-eosin (HE), Masson’s trichrome, Gomori’s reticulin stain and PAS technique. Pterygium is mostly covered by conjunctival epithelium, while in the cap region shows morphology of modifi ed stratifi ed squamous epithelium of the cornea. Structural basis of the epithelium is composed of continuous basal lamina and continuous connective fi bers underneath. Th is connective basis shows fi brinoid changes in the form of oval islets of diff erent size, parallel to convexity of pterygium, or is in the form of unifi ed focus. Th e number, caliber and the type of blood vessels showed excessive variability. Pathohistological analysis of morphological characteristics of pterygium is adequate basis for prediction of recurrences; as they present the biggest concern in treatment of this widely spread disease. © Association of Basic Medical Sciences of FBIH. All rights reserve