S BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES 20010; 10 (SUPPLEMENT 1): S56-S62

Each haemodialysis treatment requires the application of anticoagulation medicines, which will prevent coagulation in extracorporal blood circulation. In this study we try to determine the quality of admitted anticoagulant and his eff ect on lipid profi le on hemodialy-sis patients after twelth months. We were applying standard heparin and low weight molecular heparin (LWMH). During our study we was analyzed eff ect of anticoagulant therapy on lipid profi le of hemodialysis patients. In that parameters was included triglycerides, cholesterol, lipoprotein fractions, complete blood count, Hgb, HCT; All of these parameters was analyzed in correlation with dura-tion of hemodialysis treatment, sex and age of the patients. Our research was carried out as a prospective study, for the period of months. In the study were included patients (M/F), who were on chronic hemodialysis program. All patients were divided into two groups. a e fi rst group of patients was included patients (M/F) who were treated with standard heparin. a e second group was included patients (M/F) treated with LWMH (enoxaparin). a e average length of hemodialysis was , ± , years. Each patient had a protocol in which is marked parameters such as fl ushing diallysator, creating fi brin-ring in vein and arterial dropper and the time it takes to stop the bleeding. In the results the average age amounted to , ± , years. a e average value of cholesterol in the blood was , ± ,. Values of HDL-cholesterol in patients treated with LWMH were signifi cantly lower (P≤,) in the treated group compared to standard heparin. a ere were no signifi cant statistical diff erences between both groups in relation to the level of LDL cholesterol in the blood. (p ns). LWMH had a better eff ect on the irrigation system and dialysator on both se