Inference of the Plant Defense Signaling Network Based on Expression Profiles of

Short Abstract — Expression profiles can be used as detailed descriptions of the states of biological networks. To obtain expression profiles for use in inferring the topology of the plant defense signaling network, an inexpensive and accurate, small-scale microarray technology was developed. The microarray was used to screen Arabidopsis mutants for discovery of new network components. The profiles of newly-identified mutants and known mutants were used to infer the signaling network. Comparison of the bacterial growth in planta and the inferred network structure predicts a new mode of defense contributing to resistance against bacterial pathogens