Cytotoxic Activity of Enteromorpha intestinalis Extracts against Tumor Cell-Line HeLa

Two extracts (methanol and hexan) were extracted from green algae Enteromorpha intestinalis which is isolated from Basra / Iraq, the cytotoxic activity of these extracts were evaluated by using MTT assay on HeLa cells in vitro, according to the results both extracts are effectiveness on cancer cells with the superiority of methanol extract, the IC50 of methanol extract was 79.08µg/ml and 156.3µg/ml for hexan extract. Also during the current study a number of cytotoxic compounds were isolated from both algal extracts according to the chemical analysis results by using Gc mass technique, these compounds are loliolide, palmitic acid, ethyl palmitate, phytol and squalene from methanol extract while the hexane extract contains palmitic acid, ethyl palmitate and dibutyl phthalate