Int J Clin Exp Med 2015;8(9):16682-16687 www.ijcem.com /ISSN:1940-5901/IJCEM0012823 Original Article

Abstract: Background: Many studies have examined risk factors of nosocomial bloodstream infections. However risk factors of nosocomial bloodstream infections in surgical intensive care unit have never been reported. The aim of this study was to investigate this topic. Methods: Retrospective surgical intensive care unit patients ’ data were collected in a tertiary hospital from January 2010 to August 2014. Infected and non-infected patients were com-pared with univariate analysis of categorical variables to obtain statistical significance risk factors. Then multivariate logistic regression analysis was performed to acquire the final risk factors. Results: 98 patients were diagnosed with nosocomial bloodstream infections in total. Mortality rate was 29.6 % (n=29). The data indicated gram-positive cocci were the main pathogens (64.3%; n=63). Multivariate logistic analysis indicated that age (>65 years old) (OR, 2.297; CI95, 0.870 to 6.062), acute physiology and chronic health evaluation II score (>18) (OR, 6.981; CI95, 2.330 to 15.865), multiple organ dysfunction score (>8) (OR, 9.857; CI95, 6.395 to 19.505), mechanical ventilation (OR, 4.583; CI95, 2.134 to 10.956), central venous catheter (OR, 5.875; CI95, 2.212 to 13.456) and selective surgery (OR, 3.455; CI95, 3.442-9.235) were risk factors of nosocomial BSI. Conclusions: Patients with nosocomial blood-stream infections in surgical intensive care unit setting often have a poor prognosis. Age (>65 years old), chronic health evaluation II score (>18), multiple organ dysfunction score (>8), usage of mechanical ventilation, centra