Precise Predictions of Linear

cell epitopes–the part of an antigen recog-nized by an antibody–are conformational in nature; however, accurately predicting these epitopes is difficult for proteins with-out a known three-dimensional (3D) structure. DNASTAR presents the NeoClone method, a machine learning approach that improves the ability to predict linear B cell epitopes (a pep-tide segment) using only sequence-based infor-mation. This method provides better overall predictive accuracy than COBEpro and Epi-topia, two leading epitope prediction methods. Free trial software is available at dnastar.com