Hepatitis B Virus Reactivation and Prophylaxis During Solid Tumor

Background: Solid tumor chemotherapy regimens pose a risk for hepatitis B virus (HBV) reactivation, but screening and antivi-ral prophylaxis remains controversial because of insufficient evidence. Purpose: To determine the risk for HBV reactivation with and without antiviral prophylaxis and the effectiveness of prophylaxis in adults with solid tumors and chronic or resolved HBV infection