Quality Assurance

Please find the HPLC-PCOX checklist attached-word document titled “PSP HPLC PCOX checklist.docx ” There is no summary of changes as no previous checklist exists for this procedure Public Health Significance: The HPLC-PCOX method has been an approved limited use method since 2009, yet no checklist exists to allow evaluation of laboratories who utilize this method. Use of this method provides states much more detailed toxin profiles as well as helping eliminate animal testing. It is important that the checklist items and quality assurance requirements are clear and understandable. Cost Information (if available): For laboratories that do not already possess a HPLC post column reaction system, the upfront cost can be significant. Once in place, the costs per test are not significantly different than that imposed by the capital cost of the mouse bioassay