Assessment of Toxicity of Upper Danube River Sediments Using a Combination of Chemical Fractionation, the Danio rerio Embryo Assay and the Ames Fluctuation Test

Severely contaminated sediments from many rivers and lakes have been shown to be acutely and chronically toxic to fish and benthic invertebrate species. For example, sediment samples from the Upper Danube River that were analyzed in six separate assays were found to have considerable geno-toxic, cytotoxic