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Osteoporosis is the most common bone disease in humans and represents a major public health concern (1). It is characterized by low bone mass, deterioration of bone tissue and disruption of bone architecture, compromised bone strength, and an increased in the risk of fracture (2). The World Health Organization’s diagnostic classification defines osteoporosis by a bone mineral density at the hip or spine of less than 2.5 standard deviations below peak bone mass (T-score-2.5). Osteoporosis is an intermediate outcome for fractures; however, most fractures occur in patients with low bone mass rather than osteoporosis. Osteoporosis occurs most frequently in women after menopause, but can also affect men. It is the cause of most fractures in older people and is an important contributor to mortality, physical disability, and medical expense (2). While genetic predisposition, aging, and estrogen deficiency are the most common contributors, severe bone loss may also be caused by a wide variety of medical problems including rheumatoid arthritis and drugs such as corticosteroids. In these individuals, the weakening of bone may occur at a younger age, setting the stage for premature fractures and disability (3). The prevention and treatment of osteoporosis has been made possible by an increase in public and physician awareness, advances in early diagnosis using bone density measurement, an