NF-κB Inhibition

Cinobufagin, a bufadienolide from traditional Chinese medicine Bufo bufo gargarizans CANTOR, inhibits PC3 cell growth in vitro and in vivo

Tianli Niu
Liye Zhao
Xuyao Lin
Yangkai Cai
Shuhui Chen
Mingkai Wang
Li Zhou
Hongyang Ding
Xiaohan Yu
Guozheng Qin

April 2019

Objective: To explore the effects of cinobufagin (CBF), an active component of toad venom (Bufo bufo...

Coumarin polysulfides inhibit cell growth and induce apoptosis in HCT116 colon cancer cells

Nathaniel Edward Bennett Saidu
Sergio Valente
Emilie Bana
Gilbert Kirsch
Denyse Bagrel
Mathias Montenarh

January 2012

Coumarins and coumarin derivatives as well as diallyl polysulfides are well known as anticancer drug...

Antiproliferative and apoptotic effects of angelicin in highly invasive prostate cancer cells

Wang, Q
Wang, Y-P
Lin, H
Zhang, L-Q
Wu, L-J
Pang, L-X

September 2015

Purpose: To demonstrate the anti-proliferative activity of angelicin against human prostate cancer (...

NF-κB Inhibition

Mohd Rais Mustafa
Siddig Ibrahim Abdelwahab

August 2016

License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...

Dentatin Induces Apoptosis in Prostate Cancer Cells via Bcl-2, Bcl-xL, Survivin Downregulation, Caspase-9, -3/7 Activation, and NF-κB Inhibition

Arbab, I.A.
Looi, Chung Yeng
Abdul, A.B.
Cheah, F.K.
Wong, Won Fen
Sukari, M.A.
Abdullah, R.
Mohan, S.
Syam, S.
Arya, Aditya
Mustafa, Mohd Rais

January 2012

This study was set to investigate antiproliferative potential of dentatin (a natural coumarin isolat...

Characterization of dentatin isolated from Clausena excavate and its potential use for treatment of human breast and prostate cancers

Ishag, Ismail Adam Arbab

June 2012

To date, there has been no literature reported on the mechanism of dentatin and its effects on breas...

Inducing G2/M Cell Cycle Arrest and Apoptosis through Generation Reactive Oxygen Species (ROS)-Mediated Mitochondria Pathway in HT-29 Cells by Dentatin (DEN) and Dentatin Incorporated in Hydroxypropyl-β-Cyclodextrin (DEN-HPβCD)

Al-Abboodi Shakir Ashwaq
Mothanna Sadiq Al-Qubaisi
Abdullah Rasedee
Ahmad Bustamam Abdul
Yun Hin Taufiq-Yap
Swee Keong Yeap

October 2016

Dentatin (DEN), purified from the roots of Clausena excavata Burm f., has poor aqueous solubility th...

Dentatin isolated from Clausena excavata induces apoptosis in MCF-7 cells through the intrinsic pathway with involvement of NF-kB signalling and G0/G1 cell cycle arrest: A bioassay-guided approach

Arbab, I.A.
Abdul, A.B.
Sukari, M.A.
Abdullah, R.
Syam, S.
Kamalidehghan, B.
Ibrahim, M.Y.
Taha, M.M.E.
Abdelwahab, S.I.
Ali, H.M.
Mohan, S.

January 2013

Ethnopharmacological relevance: Clausena excavata Burm. f. has been used in folk medicines in easter...

Anticancer effect of dentatin and dentatin-hydroxypropyl-β-cyclodextrin complex on human colon cancer (HT-29) cell line

AL-Abboodi AS
Rasedee A
Abdul AB
Taufiq-Yap YH
Alkaby WA
Ghaji MS
Waziri PM
Al-Qubaisi MS

November 2017

Ashwaq Shakir AL-Abboodi,1,2 Abdullah Rasedee,3 Ahmad Bustamam Abdul,1,4 Yun Hin Taufiq-Yap,5 Wafaa ...

Rumex dentatus Inhibits Cell Proliferation, Arrests Cell Cycle, and Induces Apoptosis in MDA-MB-231 Cells through Suppression of the NF-κB Pathway

Riffat Batool
Ejaz Aziz
Benny K.-H. Tan
Tariq Mahmood

October 2017

Background:Rumex dentatus, commonly known as tooth docked, is widely used in traditional system of m...

Clausenidin induces caspase-dependent apoptosis in colon cancer

Waziri, Peter M.
Abdullah, Rasedee
Swee, Keong Yeap
Omar, Abdul Rahman
Kassim, Nur Kartinee
Malami, Ibrahim
Chee, Wun How
Christopher Etti, Imaobong
Abu, Mary Ladidi

January 2016

Background: Clausena excavata burm.f. Is a shrub traditionally used to treat cancer patients in asia...

Characterization and cytotoxicity of clausenidin from Clausena excavata Burm f. and its effects on cell cycle regulation and apoptosis of liver (hepg2) and colon (ht29) cancer cell lines

Waziri, Peter Maitalata

February 2017

Clausena excavata Burm. f. is a wild shrub from the Rutaceae family predominantly found in tropical ...

Argentatin B Inhibits Proliferation of Prostate and Colon Cancer Cells by Inducing Cell Senescence

Ela Alcántara-Flores

November 2015

Argentatin B has been shown to inhibit the growth of colon HCT-15, and prostate PC-3 cancer cells. H...

Pinocembrin flavanone inhibits cell viability in PC-3 human prostate cancer by inducing cellular apoptosis, ROS production and cell cycle arrest

LINHAI SHAO
YAJUN SHAO
YU YUAN

January 2021

The main purpose of the present study was to evaluate the antitumor effects of pinocembrin in human ...

Yc-1 Suppresses Constitutive Nuclear Factor-Kappa B Activation and Induces Apoptosis in Human Prostate Cancer Cells

鄧哲明
TENG, CHE-MING

December 2008

Although the indazole compound, YC-1, is reported to exert anticancer activities in several cancer c...

Cinobufagin, a bufadienolide from traditional Chinese medicine Bufo bufo gargarizans CANTOR, inhibits PC3 cell growth in vitro and in vivo

Tianli Niu
Liye Zhao
Xuyao Lin
Yangkai Cai
Shuhui Chen
Mingkai Wang
Li Zhou
Hongyang Ding
Xiaohan Yu
Guozheng Qin

April 2019

Objective: To explore the effects of cinobufagin (CBF), an active component of toad venom (Bufo bufo...

Coumarin polysulfides inhibit cell growth and induce apoptosis in HCT116 colon cancer cells

Nathaniel Edward Bennett Saidu
Sergio Valente
Emilie Bana
Gilbert Kirsch
Denyse Bagrel
Mathias Montenarh

January 2012

Coumarins and coumarin derivatives as well as diallyl polysulfides are well known as anticancer drug...

Antiproliferative and apoptotic effects of angelicin in highly invasive prostate cancer cells

Wang, Q
Wang, Y-P
Lin, H
Zhang, L-Q
Wu, L-J
Pang, L-X

September 2015

Purpose: To demonstrate the anti-proliferative activity of angelicin against human prostate cancer (...

NF-κB Inhibition

Mohd Rais Mustafa
Siddig Ibrahim Abdelwahab

August 2016

License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...

Dentatin Induces Apoptosis in Prostate Cancer Cells via Bcl-2, Bcl-xL, Survivin Downregulation, Caspase-9, -3/7 Activation, and NF-κB Inhibition

Arbab, I.A.
Looi, Chung Yeng
Abdul, A.B.
Cheah, F.K.
Wong, Won Fen
Sukari, M.A.
Abdullah, R.
Mohan, S.
Syam, S.
Arya, Aditya
Mustafa, Mohd Rais

January 2012

This study was set to investigate antiproliferative potential of dentatin (a natural coumarin isolat...

Characterization of dentatin isolated from Clausena excavate and its potential use for treatment of human breast and prostate cancers

Ishag, Ismail Adam Arbab

June 2012

To date, there has been no literature reported on the mechanism of dentatin and its effects on breas...

Inducing G2/M Cell Cycle Arrest and Apoptosis through Generation Reactive Oxygen Species (ROS)-Mediated Mitochondria Pathway in HT-29 Cells by Dentatin (DEN) and Dentatin Incorporated in Hydroxypropyl-β-Cyclodextrin (DEN-HPβCD)

Al-Abboodi Shakir Ashwaq
Mothanna Sadiq Al-Qubaisi
Abdullah Rasedee
Ahmad Bustamam Abdul
Yun Hin Taufiq-Yap
Swee Keong Yeap

October 2016

Dentatin (DEN), purified from the roots of Clausena excavata Burm f., has poor aqueous solubility th...

Dentatin isolated from Clausena excavata induces apoptosis in MCF-7 cells through the intrinsic pathway with involvement of NF-kB signalling and G0/G1 cell cycle arrest: A bioassay-guided approach

Arbab, I.A.
Abdul, A.B.
Sukari, M.A.
Abdullah, R.
Syam, S.
Kamalidehghan, B.
Ibrahim, M.Y.
Taha, M.M.E.
Abdelwahab, S.I.
Ali, H.M.
Mohan, S.

January 2013

Ethnopharmacological relevance: Clausena excavata Burm. f. has been used in folk medicines in easter...

Anticancer effect of dentatin and dentatin-hydroxypropyl-β-cyclodextrin complex on human colon cancer (HT-29) cell line

AL-Abboodi AS
Rasedee A
Abdul AB
Taufiq-Yap YH
Alkaby WA
Ghaji MS
Waziri PM
Al-Qubaisi MS

November 2017

Ashwaq Shakir AL-Abboodi,1,2 Abdullah Rasedee,3 Ahmad Bustamam Abdul,1,4 Yun Hin Taufiq-Yap,5 Wafaa ...

Rumex dentatus Inhibits Cell Proliferation, Arrests Cell Cycle, and Induces Apoptosis in MDA-MB-231 Cells through Suppression of the NF-κB Pathway

Riffat Batool
Ejaz Aziz
Benny K.-H. Tan
Tariq Mahmood

October 2017

Background:Rumex dentatus, commonly known as tooth docked, is widely used in traditional system of m...

Clausenidin induces caspase-dependent apoptosis in colon cancer

Waziri, Peter M.
Abdullah, Rasedee
Swee, Keong Yeap
Omar, Abdul Rahman
Kassim, Nur Kartinee
Malami, Ibrahim
Chee, Wun How
Christopher Etti, Imaobong
Abu, Mary Ladidi

January 2016

Background: Clausena excavata burm.f. Is a shrub traditionally used to treat cancer patients in asia...

Characterization and cytotoxicity of clausenidin from Clausena excavata Burm f. and its effects on cell cycle regulation and apoptosis of liver (hepg2) and colon (ht29) cancer cell lines

Waziri, Peter Maitalata

February 2017

Clausena excavata Burm. f. is a wild shrub from the Rutaceae family predominantly found in tropical ...

Argentatin B Inhibits Proliferation of Prostate and Colon Cancer Cells by Inducing Cell Senescence

Ela Alcántara-Flores

November 2015

Argentatin B has been shown to inhibit the growth of colon HCT-15, and prostate PC-3 cancer cells. H...

Pinocembrin flavanone inhibits cell viability in PC-3 human prostate cancer by inducing cellular apoptosis, ROS production and cell cycle arrest

LINHAI SHAO
YAJUN SHAO
YU YUAN

January 2021

The main purpose of the present study was to evaluate the antitumor effects of pinocembrin in human ...

Yc-1 Suppresses Constitutive Nuclear Factor-Kappa B Activation and Induces Apoptosis in Human Prostate Cancer Cells

鄧哲明
TENG, CHE-MING

December 2008

Although the indazole compound, YC-1, is reported to exert anticancer activities in several cancer c...

Cinobufagin, a bufadienolide from traditional Chinese medicine Bufo bufo gargarizans CANTOR, inhibits PC3 cell growth in vitro and in vivo

Tianli Niu
Liye Zhao
Xuyao Lin
Yangkai Cai
Shuhui Chen
Mingkai Wang
Li Zhou
Hongyang Ding
Xiaohan Yu
Guozheng Qin

April 2019

Objective: To explore the effects of cinobufagin (CBF), an active component of toad venom (Bufo bufo...

Coumarin polysulfides inhibit cell growth and induce apoptosis in HCT116 colon cancer cells

Nathaniel Edward Bennett Saidu
Sergio Valente
Emilie Bana
Gilbert Kirsch
Denyse Bagrel
Mathias Montenarh

January 2012

Coumarins and coumarin derivatives as well as diallyl polysulfides are well known as anticancer drug...

Antiproliferative and apoptotic effects of angelicin in highly invasive prostate cancer cells

Wang, Q
Wang, Y-P
Lin, H
Zhang, L-Q
Wu, L-J
Pang, L-X

September 2015

Purpose: To demonstrate the anti-proliferative activity of angelicin against human prostate cancer (...

NF-κB Inhibition

Abstract

Extracted data

NF-κB Inhibition

Abstract

Extracted data

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