Add to ORKGA number of interesting issues have been addressed on biological networks about their global and local properties. The connection between the topological properties of proteins in Protein-Protein Interaction (PPI) networks and their biological relevance has been investigated focusing on hubs, i.e. proteins with a large number of interacting partners. We will survey the literature trying to answer the following questions: Do hub proteins have special biological properties? Do they tend to be more essential than non-hub proteins? Are they more evolutionarily conserved? Do they play a central role in modular organization of the protein interaction network? Are there structural properties that characterize hub proteins? Key words: Protein-Prote...
<div><p>The availability of large-scale protein-protein interaction networks for numerous organisms ...
Recent studies have emphasized the value of including structural information into the topological an...
Background: In spite of the scale-free degree distribution that characterizes most protein interacti...
Hubs are proteins with a large number of interactions in a protein-protein interaction network. They...
Protein–protein interactions are usually shown as interaction networks (graphs), where the proteins ...
In spite of the scale-free degree distribution that characterizes most protein interaction networks ...
In spite of the scale-free degree distribution that characterizes most protein interaction networks ...
In spite of the scale-free degree distribution that characterizes most protein interaction networks ...
Background: In spite of the scale-free degree distribution that characterizes most protein interacti...
In the post-genomic era, a central and overarching question in the analysis of protein-protein inte...
In this thesis we propose some new approaches to the study of complex networks, and apply them to mu...
In this thesis we propose some new approaches to the study of complex networks, and apply them to mu...
degree scale that defines “hub” proteins having special topological and functional significance. Th...
In this thesis we propose some new approaches to the study of complex networks, and apply them to mu...
degree scale that defines “hub” proteins having special topological and functional significance. Th...
<div><p>The availability of large-scale protein-protein interaction networks for numerous organisms ...
Recent studies have emphasized the value of including structural information into the topological an...
Background: In spite of the scale-free degree distribution that characterizes most protein interacti...
Hubs are proteins with a large number of interactions in a protein-protein interaction network. They...
Protein–protein interactions are usually shown as interaction networks (graphs), where the proteins ...
In spite of the scale-free degree distribution that characterizes most protein interaction networks ...
In spite of the scale-free degree distribution that characterizes most protein interaction networks ...
In spite of the scale-free degree distribution that characterizes most protein interaction networks ...
Background: In spite of the scale-free degree distribution that characterizes most protein interacti...
In the post-genomic era, a central and overarching question in the analysis of protein-protein inte...
In this thesis we propose some new approaches to the study of complex networks, and apply them to mu...
In this thesis we propose some new approaches to the study of complex networks, and apply them to mu...
degree scale that defines “hub” proteins having special topological and functional significance. Th...
In this thesis we propose some new approaches to the study of complex networks, and apply them to mu...
degree scale that defines “hub” proteins having special topological and functional significance. Th...
<div><p>The availability of large-scale protein-protein interaction networks for numerous organisms ...
Recent studies have emphasized the value of including structural information into the topological an...
Background: In spite of the scale-free degree distribution that characterizes most protein interacti...