Add to ORKGBiopharmaceuticals (e.g. antibodies) by their nature are complex molecules requiring specific post-translational modifications for activity [1]. It is for this reason that these proteins are produced in mammalian expressio
Post-translational modification (PTM) refers to the covalent and enzymatic modification of proteins ...
Over the lifespan of therapeutic proteins, from the point of biosynthesis to the complete clearance ...
Biocomplexity—the study of complex structures and behaviours that take place in biological systems—g...
Whilst the amino acid sequence of a protein is determined by its gene sequence, the final structure ...
Pharmaceutical biotechnology is big business; it currently consists of 1/6 of the total volume of th...
Most functional biopharmaceuticals such as antibodies are glycoproteins carrying N-linked oligosacch...
Posttranslational modifications are a fundamental mechanism for the regulation of cellular physiolog...
One of the most important current scientific paradoxes is the economy with which nature uses genes. ...
International audienceAlthough the majority of proteins used for biomedical research are produced us...
Nature has produced intricate machinery to covalently diversify the structure of proteins after thei...
Twelve pages by Dr. James L. Harley (National Cancer Institute, Frederick, MD, USA; editor of this i...
AbstractMammalian protein production platforms have had a profound impact in many areas of basic and...
Nature has produced intricate machinery to covalently diversify the structure of proteins after thei...
Biopharmaceutical manufacturing plays a critical role in global healthcare systems. Methods and tec...
Post-translational modifications (PTMs) of proteins modulate protein activity and greatly expand the...
Post-translational modification (PTM) refers to the covalent and enzymatic modification of proteins ...
Over the lifespan of therapeutic proteins, from the point of biosynthesis to the complete clearance ...
Biocomplexity—the study of complex structures and behaviours that take place in biological systems—g...
Whilst the amino acid sequence of a protein is determined by its gene sequence, the final structure ...
Pharmaceutical biotechnology is big business; it currently consists of 1/6 of the total volume of th...
Most functional biopharmaceuticals such as antibodies are glycoproteins carrying N-linked oligosacch...
Posttranslational modifications are a fundamental mechanism for the regulation of cellular physiolog...
One of the most important current scientific paradoxes is the economy with which nature uses genes. ...
International audienceAlthough the majority of proteins used for biomedical research are produced us...
Nature has produced intricate machinery to covalently diversify the structure of proteins after thei...
Twelve pages by Dr. James L. Harley (National Cancer Institute, Frederick, MD, USA; editor of this i...
AbstractMammalian protein production platforms have had a profound impact in many areas of basic and...
Nature has produced intricate machinery to covalently diversify the structure of proteins after thei...
Biopharmaceutical manufacturing plays a critical role in global healthcare systems. Methods and tec...
Post-translational modifications (PTMs) of proteins modulate protein activity and greatly expand the...
Post-translational modification (PTM) refers to the covalent and enzymatic modification of proteins ...
Over the lifespan of therapeutic proteins, from the point of biosynthesis to the complete clearance ...
Biocomplexity—the study of complex structures and behaviours that take place in biological systems—g...