Microscope Evanescent Wave Imaging Systems

Simple and fast switching between the epi-fluorescence and two types of TIRF methods—laser or white-light. Cellular focal adhesion images can be acquired with excellent S/N ratios TIRF (Total Internal Reflection Fluorescence) microscopy facilitates extremely high-sensitivity and high-contrast visualization of single molecules near the coverglass, without disturbing cellular activity, thereby enabling the tracking of biomolecules, and the study of their dynamic activity and interactions at the molecular level. Nikon’s laser TIRF-2 system integrates a laser TIRF system and epi-fluorescence system, while the white-light TIRF system shares the mercury lamp of the epi-fluorescence system, and enables oblique and TIR illumination. Both TIRF systems can also accommodate confocal, laser tweezers and other modules thanks to the expandable stratum structure of the TE2000 Inverted Microscope. Nikon’s TIRF series dramatically expands the boundaries of what is possible in bioscience research, and is the perfect tool for scientists exploring molecular dynamics