Abstract. We present and study the behavior of a simple kinetic model for the melting of RNA secondary struc-tures, given that those structures are known. The model is then used as a map that assigns tructure dependent overall rate constants of melting (or refolding) to a se-quence. This induces a "landscape " of reaction rates, or activation energies, over the space of sequences with fixed length. We study the distribution and the correlation structure of these activation energies. Key words: Activation energy landscape- RNA folding- RNA melting- RNA secondary structure 1
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI--COLUMBIA AT REQUEST OF AUTHOR.] RNA (Ribonucleic a...
MOTIVATION: Many computational methods for RNA secondary structure prediction, and, in particular, f...
<div><p>The folding of linear polymers into discrete three-dimensional structures is often required ...
We study the stochastic folding kinetics of RNA sequences into secondary structures with a new algor...
It has recently been found that some RNA functions are determined by the actual folding kinetics and...
Dynamical changes of RNA secondary structures play an important role in the function of many regulat...
It has recently been found that some RNA functions are determined by the actual folding kinetics and...
The ability to fold into well-defined native conformation is a prerequisite for biologically functio...
This thesis examines nucleic acid folding processes using secondary structure models, which have the...
Dynamical changes of RNA secondary structures play an important role in the function of many regulat...
We discuss the physics of RNA as described by its secondary structure. We examine the static propert...
A neighbor of the RNA secondary structure s is obtained by removing, adding or shifting a base pair ...
AbstractWe report a new computational approach to the prediction of RNA secondary structure folding ...
International audienceMotivation: Kinetics is key to understand many phenomena involving RNAs, such ...
AbstractBased on an ensemble of kinetically accessible conformations, we propose a new analytical mo...
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI--COLUMBIA AT REQUEST OF AUTHOR.] RNA (Ribonucleic a...
MOTIVATION: Many computational methods for RNA secondary structure prediction, and, in particular, f...
<div><p>The folding of linear polymers into discrete three-dimensional structures is often required ...
We study the stochastic folding kinetics of RNA sequences into secondary structures with a new algor...
It has recently been found that some RNA functions are determined by the actual folding kinetics and...
Dynamical changes of RNA secondary structures play an important role in the function of many regulat...
It has recently been found that some RNA functions are determined by the actual folding kinetics and...
The ability to fold into well-defined native conformation is a prerequisite for biologically functio...
This thesis examines nucleic acid folding processes using secondary structure models, which have the...
Dynamical changes of RNA secondary structures play an important role in the function of many regulat...
We discuss the physics of RNA as described by its secondary structure. We examine the static propert...
A neighbor of the RNA secondary structure s is obtained by removing, adding or shifting a base pair ...
AbstractWe report a new computational approach to the prediction of RNA secondary structure folding ...
International audienceMotivation: Kinetics is key to understand many phenomena involving RNAs, such ...
AbstractBased on an ensemble of kinetically accessible conformations, we propose a new analytical mo...
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI--COLUMBIA AT REQUEST OF AUTHOR.] RNA (Ribonucleic a...
MOTIVATION: Many computational methods for RNA secondary structure prediction, and, in particular, f...
<div><p>The folding of linear polymers into discrete three-dimensional structures is often required ...