gramming in the Enterprise-wide Optimization of Process Industries

Enterprise-wide optimization (EWO) is a new emerging area that lies at the interface of chemical engineering and operations research, and has become a major goal in the process industries due to the increasing pressures for remaining competitive in the global marketplace. EWO involves optimizing the operations of supply, production and distribu-tion activities of a company to reduce costs and inventories. A major focus in EWO is the optimization of manufacturing plants as part of the overall optimization of the supply chain. Major operational items in-clude production planning, scheduling, and control. This talk provides an overview of major modeling and computational challenges in the development of deterministic and stochastic linear/nonlinear mixed-integer optimization models for planning and scheduling for the opti-mization of plants and entire supply chains that are involved in EWO problems. We illustrate the application of these ideas in four major problems: a) integration of planning and scheduling in batch processe