Ovarian responses after superovulation with different dosages of oFSH in goats

A total of 35 crossbred goats (Capra hircus) were used to evaluate the effect of oFSH dosages on ovarian responses during superovulation. A controlled internal drug release (CIDR) was inserted for 14 days in each goat. The animals were divided into 3 groups. Groups M1 and M2 received 8.8 mg and 14.08 mg, respectively, of oFSH through multiple intramuscular (i.m.) injections starting from 2 days before the CIDR removal and Group S received 8.8 mg of oFSH through a single i.m. injection upon CIDR removal. Ovarian responses of all treatments were evaluated during laparotomy session on Day 3 or 7 after CIDR removal. All of the does (100%, 22/22) of Groups M1 and M2 responded positively to the treatments by ovulating at least 1 tertiary follicle. On the other hand, only 69 % (9/13) of the does of Group S responded correspondingly to the treatment. The total ovarian responses (CL plus anovulatory follicles) among the treatments were significantly higher (P<0.05) in Groups M1 and M2 compared with Group S. There were no significant differences between multiple-administration groups for CL per doe (high dosages vs. low dosages: 16.9±3.9 vs. 11.6±1.0, respectively). The percentage of anovulatory follicles wa