References

Necropsy (viewing the dead) refers to the post mortem examination of organs and tissues (autopsy = self + view). A useful technique should efficiently evaluate all organs and lesions, and be teachable and reproducible. A checklist can help to ensure that all procedures are performed (e.g., photography, radiography, and gross necropsy), and that all tissues are examined, weighed or measured. There are many necropsy techniques. Variations can be justified by specific aims or requirements of a diagnostic procedure or research study. However a standardized systematic procedure, to which minor variations can be made, can improve comparisons within and between studies, even when initial examinations are months or years apart. [1] [2] [3] [4] [5] Strategic use of pathology in research settings can include clinical and anatomic pathology to: 1. Assess disease problems, including decreased production, in breeding colonies; 2. Assess disease problems in research animals during studies; 3. Confirm and characterize phenotypes or other research endpoints; 4. Characterize and validate translational research models Equipment and Material