Add to ORKGAbstract An expanding assortment of small, noncoding RNAs identified in the nervous system suggests a strong connection between their combinatorial regulatory potential and the complexity of the nervous system. Misregulation of these small regulatory RNAs could contribute to the abnormalities in brain development that are associated with neurodevelopmental disorders. Here we give an overview of the diversity and unexpected abundance of small RNAs, as well as specific examples that illustrate their functional significance in neurodevelopmental disorders. We also discuss an intriguing, albeit elusive area of study: the potential impact of newly discovered classes of small RNAs in the nervous system
Post-transcriptional regulation of gene expression is required for multiple aspects of neuronal deve...
The brain is of bewildering complexity and numerous genes and signaling molecules have been describe...
The human brain is one of the most complex biological systems, and the cognitive abilities have grea...
Increasingly complex networks of small RNAs act through RNA interference pathway to regulate gene ex...
Increasingly complex networks of small RNAs act through RNA interference pathway to regulate gene ex...
Small RNA is a variable and abundant type of non-coding RNAs in brain. The function of these RNAs is...
Increasing evidence suggests that the development and function of the nervous system is heavily depe...
Genomic studies in model organisms and in humans have shown that complexity in biological systems ar...
Until about a decade ago, the non-coding part of the genome was considered without function. RNA seq...
Until about a decade ago, the non-coding part of the genome was considered without function. RNA seq...
Small non coding RNAs are a group of very different RNA molecules, present in virtually all cells, w...
Abstract MicroRNAs (miRNAs) are a recently discov-ered class of small RNA molecules implicated in a ...
Small non-coding RNAs are essential for transcription, translation and gene regulation in all cell t...
The importance of various classes of regulatory non-protein-coding RNA molecules (ncRNAs) in the nor...
Nervous system is characterized by its uniqueness in cells origin, their variability, electrical pro...
Post-transcriptional regulation of gene expression is required for multiple aspects of neuronal deve...
The brain is of bewildering complexity and numerous genes and signaling molecules have been describe...
The human brain is one of the most complex biological systems, and the cognitive abilities have grea...
Increasingly complex networks of small RNAs act through RNA interference pathway to regulate gene ex...
Increasingly complex networks of small RNAs act through RNA interference pathway to regulate gene ex...
Small RNA is a variable and abundant type of non-coding RNAs in brain. The function of these RNAs is...
Increasing evidence suggests that the development and function of the nervous system is heavily depe...
Genomic studies in model organisms and in humans have shown that complexity in biological systems ar...
Until about a decade ago, the non-coding part of the genome was considered without function. RNA seq...
Until about a decade ago, the non-coding part of the genome was considered without function. RNA seq...
Small non coding RNAs are a group of very different RNA molecules, present in virtually all cells, w...
Abstract MicroRNAs (miRNAs) are a recently discov-ered class of small RNA molecules implicated in a ...
Small non-coding RNAs are essential for transcription, translation and gene regulation in all cell t...
The importance of various classes of regulatory non-protein-coding RNA molecules (ncRNAs) in the nor...
Nervous system is characterized by its uniqueness in cells origin, their variability, electrical pro...
Post-transcriptional regulation of gene expression is required for multiple aspects of neuronal deve...
The brain is of bewildering complexity and numerous genes and signaling molecules have been describe...
The human brain is one of the most complex biological systems, and the cognitive abilities have grea...