Abstract: While non-blood cell lineage has been studied for decades by developmental biologists, only recently has it been considered in disease. This is partly due to a lack of suitable reagents in experimental models, but it is also the result of a failure to understand the ability of cells to move or differentiate in pathological environments. This Editorial gives a quick overview of the Special Issue “Cell Fate Decisions in Development and Disease ” and underscores the importance of understanding the mechanisms of cell fate determination and lineage
Cell fate determination is a fundamental aspect of development and tissue homeostasis, orchestrated ...
Every cell in the body arises from a single fertilized cell that, through many cell divisions and tr...
The separation of inner cell mass and trophectoderm is the first cell fate specification event in ma...
While non-blood cell lineage has been studied for decades by developmental biologists, only recently...
The fundamental question of how an undifferentiated progenitor cell adopts a more specialized cell f...
It seems that growth factors may instruct blood-cell progenitors to develop into specific mature cel...
Evidence from studies of the behaviour of stem and progenitor cells and of the influence of cytokine...
Correct and timely lineage decisions are critical for normal embryonic development and homeostasis o...
Correct and timely lineage decisions are critical for normal embryonic development and homeostasis o...
How organ morphogenesis specifies cell fate and whether organ progenitors are predetermined or speci...
Ontologies of living things are increasingly grounded on the concepts and practices of current life ...
Cellular differentiation is a common underlying feature of all multicellularorganisms through which ...
One of the major goals of developmental biology is to elucidate the lineage relationships between po...
Reconstructing the lineage of cells is central to understanding development and is now also an impor...
Blood stem cells need to both perpetuate themselves (self-renew) and differentiate into all mature b...
Cell fate determination is a fundamental aspect of development and tissue homeostasis, orchestrated ...
Every cell in the body arises from a single fertilized cell that, through many cell divisions and tr...
The separation of inner cell mass and trophectoderm is the first cell fate specification event in ma...
While non-blood cell lineage has been studied for decades by developmental biologists, only recently...
The fundamental question of how an undifferentiated progenitor cell adopts a more specialized cell f...
It seems that growth factors may instruct blood-cell progenitors to develop into specific mature cel...
Evidence from studies of the behaviour of stem and progenitor cells and of the influence of cytokine...
Correct and timely lineage decisions are critical for normal embryonic development and homeostasis o...
Correct and timely lineage decisions are critical for normal embryonic development and homeostasis o...
How organ morphogenesis specifies cell fate and whether organ progenitors are predetermined or speci...
Ontologies of living things are increasingly grounded on the concepts and practices of current life ...
Cellular differentiation is a common underlying feature of all multicellularorganisms through which ...
One of the major goals of developmental biology is to elucidate the lineage relationships between po...
Reconstructing the lineage of cells is central to understanding development and is now also an impor...
Blood stem cells need to both perpetuate themselves (self-renew) and differentiate into all mature b...
Cell fate determination is a fundamental aspect of development and tissue homeostasis, orchestrated ...
Every cell in the body arises from a single fertilized cell that, through many cell divisions and tr...
The separation of inner cell mass and trophectoderm is the first cell fate specification event in ma...