Add to ORKGAbstract: MiR-122 is a novel tumor suppresser and its expression induces cell cycle arrest, or apoptosis, and inhibits cell proliferation in multiple cancer cells, including non-small cell lung cancer (NSCLC) cells. Radioresistance of cancer cell leads to the major drawback of radiotherapy for NSCLC and the induction of radiosensitization could be a useful strategy to fix this problem. The present work investigates the function of miR-122 in inducing radiosensitization in A549 cell, a type of NSCLC cells. MiR-122 induces the radiosensitization of A549 cells. MiR-122 also boosts the inhibitory activity of ionizing radiation (IR) on cancer cell anchor-independent growth and invasion. Moreover, miR-122 reduced the expression of its targeted ge...
Purpose: The oncogenic miR-155 is upregulated in many human cancers, and its expression is increased...
Radiotherapy plays an essential primary role in cancer patients. Regardless of its significant advan...
MicroRNAs play important roles in carcinogenesis and tumor progress. Lung cancer is the leading caus...
MiR-122 is a novel tumor suppresser and its expression induces cell cycle arrest, or apoptosis, and ...
MiR-122 is a novel tumor suppresser and its expression induces cell cycle arrest, or apoptosis, and ...
Background/Aims: A growing body of evidence indicates that the abnormal expression of microRNAs (miR...
MicroRNAs (miRNAs or miRs) regulate gene expression at the posttranscriptional level and are involve...
Copyright © 2014 Yongfu Ma et al. This is an open access article distributed under the Creative Comm...
Copyright © 2015 Yan-mei Xu et al. This is an open access article distributed under the Creative Com...
The present study aimed to define the tumor-suppressive role of microRNA-499 (miR-499) in lung cance...
Background/Aims: Numerous studies have demonstrated that aberrant microRNA (miRNA) expression is inv...
Recent studies have revealed that microRNAs regulate radiosensitivity of non-small cell lung cancer ...
Background/Aims: Radiation therapy is an important and effective modality for the treatment of non-s...
Radiotherapy (RT) is a key therapeutic strategy for lung cancer, the most common cause of cancer-rel...
Purpose: The oncogenic miR-155 is upregulated in many human cancers, and its expression is increased...
Purpose: The oncogenic miR-155 is upregulated in many human cancers, and its expression is increased...
Radiotherapy plays an essential primary role in cancer patients. Regardless of its significant advan...
MicroRNAs play important roles in carcinogenesis and tumor progress. Lung cancer is the leading caus...
MiR-122 is a novel tumor suppresser and its expression induces cell cycle arrest, or apoptosis, and ...
MiR-122 is a novel tumor suppresser and its expression induces cell cycle arrest, or apoptosis, and ...
Background/Aims: A growing body of evidence indicates that the abnormal expression of microRNAs (miR...
MicroRNAs (miRNAs or miRs) regulate gene expression at the posttranscriptional level and are involve...
Copyright © 2014 Yongfu Ma et al. This is an open access article distributed under the Creative Comm...
Copyright © 2015 Yan-mei Xu et al. This is an open access article distributed under the Creative Com...
The present study aimed to define the tumor-suppressive role of microRNA-499 (miR-499) in lung cance...
Background/Aims: Numerous studies have demonstrated that aberrant microRNA (miRNA) expression is inv...
Recent studies have revealed that microRNAs regulate radiosensitivity of non-small cell lung cancer ...
Background/Aims: Radiation therapy is an important and effective modality for the treatment of non-s...
Radiotherapy (RT) is a key therapeutic strategy for lung cancer, the most common cause of cancer-rel...
Purpose: The oncogenic miR-155 is upregulated in many human cancers, and its expression is increased...
Purpose: The oncogenic miR-155 is upregulated in many human cancers, and its expression is increased...
Radiotherapy plays an essential primary role in cancer patients. Regardless of its significant advan...
MicroRNAs play important roles in carcinogenesis and tumor progress. Lung cancer is the leading caus...