Survival and Long-termOutcomes Following Bioprosthetic vsMechanical Aortic Valve Replacement in Patients Aged 50 to 69 Years

IMPORTANCE The choice between bioprosthetic andmechanical aortic valve replacement in younger patients is controversial because long-term survival andmajor morbidity are poorly characterized. OBJECTIVE To quantify survival andmajor morbidity in patients aged 50 to 69 years undergoing aortic valve replacement. DESIGN, SETTING, AND PARTICIPANTS Retrospective cohort analysis of 4253 patients aged 50 to 69 years who underwent primary isolated aortic valve replacement usin