REMICADE @ (infliximab) is a chimeric 1gGl ~ monoclonal antibody with an approximate molecular weight of 149,100 daltons. It is composed of human constant and murine variable regions. Infliximab binds specifically to human tumor necrosis factor alpha (TNFa) with an association constant of 10 ” M’. Infliximab is produced by a recombinant cell line cultured by continuous perfusion and is purified by a series of steps that includes measures to inactivate and remove viruses. REMICADE is supplied as a sterile, white, lyophilized powder for intravenous infusion. Following reconstitution with 10 mL of Sterile Water for Injection, USP, the resulting pH is approximately 7.2. Each single-use vial contains 100 mg infliximab, 500 mg sucrose, 0.5 mg pol...
BACKGROUND: Tumour necrosis factor-alpha (TNFα) has an important role in the pathogenesis of inflamm...
Infliximab is an accepted induction and maintenance treatment for patients with Crohn's disease. The...
Introduction Infliximab (Remicade, Centocor, Inc., Malvern, PA), a chimeric monoclonal antibody der...
Biopharmaceuticals or 'biologics' have revolutionized the treatment of many diseases. However, some ...
(infliximab), a tumour necrosis factor-α (TNF-α) antagonist, is used in the treatment of rheumatoid ...
Item does not contain fulltextInfliximab is an accepted induction and maintenance treatment for pati...
227 Tumor necrosis factor-alpha (TNF-a.) is an inflammatory cytokine that is important in the inflam...
Therapeutic strategies that aim to neutralise the important pro-inflammatory cytokine tumour necrosi...
(See the editorial commentary by Keane on pages 300–2) Infliximab, a tumor necrosis factor (TNF) ant...
Infliximab is a chimeric anti-tumour necrosis factor-alpha monoclonal antibody that has been studied...
Anti-tumor necrosis factor-α (TNF-α) biological agents, including soluble TNF-α receptors and anti-T...
Corticosteroids and cytotoxic drugs form the conventional immunomodulators in rheumatology. This the...
Infliximab is a TNF-alpha inhibitor in the form of a chimeric monoclonal antibody. It received FDA a...
Introduction: TNF-α inhibitors can be administered either as monotherapy or in combination with othe...
Anti-tumour necrosis factor (TNF) monoclonal antibodies or soluble TNF receptors have become an inva...
BACKGROUND: Tumour necrosis factor-alpha (TNFα) has an important role in the pathogenesis of inflamm...
Infliximab is an accepted induction and maintenance treatment for patients with Crohn's disease. The...
Introduction Infliximab (Remicade, Centocor, Inc., Malvern, PA), a chimeric monoclonal antibody der...
Biopharmaceuticals or 'biologics' have revolutionized the treatment of many diseases. However, some ...
(infliximab), a tumour necrosis factor-α (TNF-α) antagonist, is used in the treatment of rheumatoid ...
Item does not contain fulltextInfliximab is an accepted induction and maintenance treatment for pati...
227 Tumor necrosis factor-alpha (TNF-a.) is an inflammatory cytokine that is important in the inflam...
Therapeutic strategies that aim to neutralise the important pro-inflammatory cytokine tumour necrosi...
(See the editorial commentary by Keane on pages 300–2) Infliximab, a tumor necrosis factor (TNF) ant...
Infliximab is a chimeric anti-tumour necrosis factor-alpha monoclonal antibody that has been studied...
Anti-tumor necrosis factor-α (TNF-α) biological agents, including soluble TNF-α receptors and anti-T...
Corticosteroids and cytotoxic drugs form the conventional immunomodulators in rheumatology. This the...
Infliximab is a TNF-alpha inhibitor in the form of a chimeric monoclonal antibody. It received FDA a...
Introduction: TNF-α inhibitors can be administered either as monotherapy or in combination with othe...
Anti-tumour necrosis factor (TNF) monoclonal antibodies or soluble TNF receptors have become an inva...
BACKGROUND: Tumour necrosis factor-alpha (TNFα) has an important role in the pathogenesis of inflamm...
Infliximab is an accepted induction and maintenance treatment for patients with Crohn's disease. The...
Introduction Infliximab (Remicade, Centocor, Inc., Malvern, PA), a chimeric monoclonal antibody der...