Description: Update of the 2003 U.S. Preventive Services Task

Force (USPSTF) recommendation statement on screening for cervi-cal cancer. Methods: The USPSTF reviewed new evidence on the comparative test performance of liquid-based cytology and the benefits and harms of human papillomavirus (HPV) testing as a stand-alone test or in combination with cytology. In addition to the systematic evidence review, the USPSTF commissioned a decision analysis to help clarify the age at which to begin and end screening, the optimal interval for screening, and the relative benefits and harms of different strategies for screening (such as cytology and co-testing). Recommendations: This recommendation statement applies to women who have a cervix, regardless of sexual history. This rec-ommendation statement does not apply to women who have re-ceived a diagnosis of a high-grade precancerous cervical lesion o