Total antioxidant capacity among diabetic patients: relationship to cardiorespiratory fitness

ABSTRACT: Regular physical activity is recognized as a non-pharmacological treatment in type II diabetes of metabolic syndrome. This study was designed to test whether aerobic capacity or cardiorespiratory fitness is associated with total antioxidant capacity in diabetes patients. Subjects were twenty six sedentary men aged 42.9 ± 5.5 year and body weight 90 ± 5.79 kg with type II diabetes that participated in study by voluntary. Total antioxidant capacity, glucose and insulin were measured after overnight fast, Cardiorespiratory fitness (VO2max) was measured using a bicycle ergometer according to YMCA protocol. Pearson correlation was used to determine the association between variables. A P-value of < 0.05 was considered to be statistically significant. No significant correlation was observed between VO2max and total antioxidant capacity in studied patients (p = 0.76, r = 0.06). Based on these data, it is concluded that antioxidant system can not affect cardiorespiratory fitness in diabetes patients, although future studies should examine the potential role of aerobic capacity or physical fitness in systemic inflammation or immune system in diabetes or other chronic diseases