Measurements: Comparison of age-at-diagnosis distributions for

Background: Studies have reported young ages at cancer diagnosis in HIV-infected persons and have suggested that HIV accelerates carcinogenesis. However, these comparisons did not account for differences in population age structures. Objective: To compare ages at diagnosis for non–AIDS-defining types of cancer that occur in both the AIDS and general popula-tions, after adjustment for differences in age and other demo-graphic characteristics between these populations. Design: Registry linkage study. Setting: 15 HIV/AIDS and cancer registry databases in the Unite