Abstract Osteogenic protein-1 is evolving as a potential bone graft alternative. Surgical site retention is important to maximize local osteoinduction and to limit peripheral effects. An established rabbit lumbar posterolateral fusion model was used to evaluate the systemic distribution and pharmacokinetics of locally applied osteogenic protein-1 delivered on a collagen carrier. L5-L6 intertransverse process fusions were performed on 27 New Zealand White rabbits. Radiolabeled 125I-osteogenic protein-1 collagen putty was implanted. At intervals, whole blood, plasma, and excreta were analyzed for radioactivity with liquid scintillation counting. Surgical site and tissue radioactivity also were assessed by quantitative whole-body autoradio-lum...
Posterolateral lumbar fusion (PLF) is a commonly performed surgical procedure for the treatment of p...
The purpose of this study was to evaluate the efficacy of recombinant human osteogenic protein-1 (rh...
To achieve an easily established, safe, and reproducible animal model for the study of heterotopic b...
The purpose of this study was to characterize the retention kinetics of recombinant human bone morph...
ABSTRACE A rabbit ulnar non-union model was used to evaluate the effect of recombinant human os-teog...
Study Design. A rabbit posterolateral intertransverse process fusion model was used to evaluate the ...
Bone morphogenetic proteins (BMPs) need an effective delivery system for efficient bone regeneration...
Compression and displacement of the developing fusion mass by the paraspinal musculature may be a co...
ABSTRACT BMP2 and BMP7, which use bovine Achilles tendon–derived absorbable collagen sponge and bovi...
Delaying of bone fusion in osteoporotic patients underwent spinal stabilization surgery leads to scr...
The study reported describes a combination of recombinant human bone morphogenetic protein-2 (rhBMP-...
PURPOSE: To evaluate the osteo-regenerative capacity of two proprietary bone grafting materials, usi...
Objective: The objective of the study was to evaluate tissue reactions such as bone genesis, cartila...
Purpose: The stability of graft material and membrane is crucial for successful guided bone regenera...
Purpose: This study aims to validate the effect of autoclaved autogenous bone (AAB), incorporating ...
Posterolateral lumbar fusion (PLF) is a commonly performed surgical procedure for the treatment of p...
The purpose of this study was to evaluate the efficacy of recombinant human osteogenic protein-1 (rh...
To achieve an easily established, safe, and reproducible animal model for the study of heterotopic b...
The purpose of this study was to characterize the retention kinetics of recombinant human bone morph...
ABSTRACE A rabbit ulnar non-union model was used to evaluate the effect of recombinant human os-teog...
Study Design. A rabbit posterolateral intertransverse process fusion model was used to evaluate the ...
Bone morphogenetic proteins (BMPs) need an effective delivery system for efficient bone regeneration...
Compression and displacement of the developing fusion mass by the paraspinal musculature may be a co...
ABSTRACT BMP2 and BMP7, which use bovine Achilles tendon–derived absorbable collagen sponge and bovi...
Delaying of bone fusion in osteoporotic patients underwent spinal stabilization surgery leads to scr...
The study reported describes a combination of recombinant human bone morphogenetic protein-2 (rhBMP-...
PURPOSE: To evaluate the osteo-regenerative capacity of two proprietary bone grafting materials, usi...
Objective: The objective of the study was to evaluate tissue reactions such as bone genesis, cartila...
Purpose: The stability of graft material and membrane is crucial for successful guided bone regenera...
Purpose: This study aims to validate the effect of autoclaved autogenous bone (AAB), incorporating ...
Posterolateral lumbar fusion (PLF) is a commonly performed surgical procedure for the treatment of p...
The purpose of this study was to evaluate the efficacy of recombinant human osteogenic protein-1 (rh...
To achieve an easily established, safe, and reproducible animal model for the study of heterotopic b...