Add to ORKGABSTRACT: Expanding the synthetic biology of artificially expanded genetic information systems (AEGIS) requires tools to make and analyze RNA molecules having added nucleotide “letters”. We report here the development of T7 RNA polymerase and reverse transcriptase to catalyze transcription and reverse transcription of xNA (DNA or RNA) having two complementary AEGIS nucleobases, 6-amino-5-nitropyridin-2-one (trivially, Z) and 2-aminoimidazo[1,2a]-1,3,5-triazin
International audienceAn RNA/protein world (probably cellular) is widely accepted as a probable step...
textThe study of biology has undergone a fundamental change due to advancements in genetic engineeri...
selection of aptamers for enhancing their drug-like character and abolishing the need for time cons...
Expanding the synthetic biology of artificially expanded genetic information systems (AEGIS) require...
ABSTRACT: Rearranging hydrogen bonding groups adds nucleobases to an artificially expanded genetic i...
The emerging field of synthetic genetics provides an opportunity to explore the structural and funct...
Rearranging hydrogen bonding groups adds nucleobases to an artificially expanded genetic information...
Beyond the natural nucleic acids DNA and RNA, nucleic acid chemistry has unlocked a whole universe o...
Impressive advances in the field of synthetic biology go hand in hand with the discovery, design, an...
Background: Modified nucleotides are increasingly being utilized in the de novo selection of aptamer...
The reverse transcription of the genetic code of an RNA molecule back into a complementary DNA copy ...
Solving the structure of DNA in 1953 has unleashed a tour de force in molecular biology that has ill...
textIn this work, we seek to expand synthetic in vitro biological systems by using water-in-oil emul...
DNA and RNA are among the most remarkable biomolecules occurring in nature. They store and transfer ...
(A) Schematic diagrams of synthetic transcription cassettes expressing pegRNAs and epegRNAs (tmpknot...
International audienceAn RNA/protein world (probably cellular) is widely accepted as a probable step...
textThe study of biology has undergone a fundamental change due to advancements in genetic engineeri...
selection of aptamers for enhancing their drug-like character and abolishing the need for time cons...
Expanding the synthetic biology of artificially expanded genetic information systems (AEGIS) require...
ABSTRACT: Rearranging hydrogen bonding groups adds nucleobases to an artificially expanded genetic i...
The emerging field of synthetic genetics provides an opportunity to explore the structural and funct...
Rearranging hydrogen bonding groups adds nucleobases to an artificially expanded genetic information...
Beyond the natural nucleic acids DNA and RNA, nucleic acid chemistry has unlocked a whole universe o...
Impressive advances in the field of synthetic biology go hand in hand with the discovery, design, an...
Background: Modified nucleotides are increasingly being utilized in the de novo selection of aptamer...
The reverse transcription of the genetic code of an RNA molecule back into a complementary DNA copy ...
Solving the structure of DNA in 1953 has unleashed a tour de force in molecular biology that has ill...
textIn this work, we seek to expand synthetic in vitro biological systems by using water-in-oil emul...
DNA and RNA are among the most remarkable biomolecules occurring in nature. They store and transfer ...
(A) Schematic diagrams of synthetic transcription cassettes expressing pegRNAs and epegRNAs (tmpknot...
International audienceAn RNA/protein world (probably cellular) is widely accepted as a probable step...
textThe study of biology has undergone a fundamental change due to advancements in genetic engineeri...
selection of aptamers for enhancing their drug-like character and abolishing the need for time cons...