Clearing Up Cardiorenal Confusion Timely

diagnosis of cardiac injury is necessary to limitthe extent of myocardial damage and to prevent and treat complications. Because cardiac injury involves dis-ruption of myocytes, the diagnosis of acute myocardial in-farction has relied on the measurement of released cellular components and the presence of symptoms and electrocar-diographic abnormalities. Previously used markers, such as creatine kinase, myoglobin, and lactate dehydrogenase, are also present in some noncardiac tissues, which limits their sensitivity and specificity. In contrast, cardiac troponins (troponin I and troponin T) are proteins that regulate muscle contraction and are found almost exclusively in the heart. Therefore, they are the most useful biomarkers of cardiac injury currently available (1). The widespread use of troponin measurement has cre-ated 2 new challenges with particular relevance to patient