Clinical Prediction Guide Adding

renal dysfunction to CHADS2 did not improve prediction of stroke or systemic embolism in AF Piccini JP, Stevens SR, Chang Y, et al. Renal dysfunction as a predictor of stroke and systemic embolism in patients with nonvalvular atrial fibrillation: validation of the R2CHADS2 index in the ROCKET and ATRIA study cohorts. Circulation. 2013;127:224-32. Clinical impact ratings: C n N Question In patients with atrial fibrillation (AF), does adding renal function to the CHADS2 score improve prediction of stroke or systemic embolism? Method