Two Self-management Interventions to Improve Hypertension Control A Randomized Trial

Background: Fewer than 40 % of persons with hypertension in the United States have adequate blood pressure (BP) control. Objective: To compare 2 self-management interventions for im-proving BP control among hypertensive patients. Design: A 2 2 randomized trial, stratified by enrollment site and patient health literacy status, with 2-year follow-up. (ClinicalTrials.gov registration number: NCT00123058) Setting: 2 university-affiliated primary care clinics. Patients: 636 hypertensive patients. Intervention: A centralized, blinded, and stratified randomization algorithm was used to randomly assign eligible patients to receive usual care, a behavioral intervention (bimonthly tailored, nurse-administered telephone intervention targeting hypertension-related behaviors), home BP monitoring 3 times weekly, or the behavioral intervention plus home BP monitoring. Measurements: The primary outcome was BP control at 6-mont