> Recommendation: Insufficient evidence for population based screening. Method of screening

CA125 have been suggested, however none of these have the sensitivity or specificity to be recommended as a screening test and can be associated with significant harms, and there is no evidence that their use for screening is effective in reducing mortality. Who should be screened? Screening is not recommended for all women. Women at potentially high risk of ovarian cancer and perhaps other cancers comprise 1 % of the population. These women should be referred to a familial cancer clinic for assessment of clinical risk and advice on risk reduction strategies and surveillance for other relevant cancers (such as bowel or breast cancer). This group comprises women with the following: • one first-degree relative diagnosed with epithelial ovaria