Review Article MAGNETIC MICROSPHERES AS A TARGETED DRUG DELIVERY SYSTEM: AN

Magnetic microspheres as an alternative to traditional radiation methods which use highly penetrating radiation that is absorbed throughout the body. The in-vivo targeting of tumors with magnetic microspheres is currently realized through the application of external non-uniform magnetic fields generated by rare-earth permanent magnets or electromagnets. Magnetically controlled drug targeting is one of the various possible ways of drug targeting. There has been keen interest in the development of a magnetically target drug delivery system. These drug delivery systems aims to deliver the drug at a rate directed by the needs of the body during the period of treatment, and target the activity entity to the site of action. Its use is limited by toxicity and side effects. The aim of the specific targeting is to enhance the efficiency of drug delivery & at the same time to reduce the toxicity & side effects. This paper gives an overview of the mechanism, benefits, drawbacks, preparation and applications of magnetic microspheres