Volume xx (200y), Number z, pp. 1–14 Robust Detection and Segmentation for Diagnosis of Vertebral Diseases using Routine MR Images

The diagnosis of certain spine pathologies, such as scoliosis, spondylolisthesis and vertebral fractures, are part of the daily clinical routine. Very frequently, MRI data are used to diagnose these kinds of pathologies in order to avoid exposing patients to harmful radiation, like X-ray. We present a method which detects and segments all acquired vertebral bodies, with minimal user intervention. This allows an automatic diagnosis to detect scoliosis, spondylolisthesis and crushed vertebrae. Our approach consists of three major steps. First, vertebral centers are detected using a Viola-Jones like method, then the ver-tebrae are segmented in a parallel manner and, finally, geometric diagnostic features are deduced in order to diagnose the three diseases. Our method was evaluated on 26 lumbar datasets containing 234 reference vertebrae. Vertebra detection has 7.1 % false negatives and 1.3 % false positives. The average Dice coefficient to manual reference is 79.3 % and mean distance error is 1.76 mm. No severe case of the 3 illnesses was missed, and false alarms occurred rarely – 0 % for scoliosis, 3.9 % for spondylolisthesis and 2.6 % for vertebral fractures. The main advantages of our method are high speed, robust handling of a large variety of routine clinical images, and simple and minimal user interaction