Graft-Versus-Host Disease of the Upper Gastrointestinal Tract After an Autologous Stem Cell Transplant

Graft-versus-host disease (GVHD) in recipients of autologous stem cell transplantation (SCT) is less common com-pared to recipients of allogeneic SCT, but its existence has been well documented. Similarly, the diarrheal com-ponent of the disease is highlighted when discussing its gastrointestinal (GI) manifestations, with less emphasis given to upper GI symptoms like nausea and vomiting. We present a case illustrating the upper GI tract signs and symptoms of GVHD after autologous SCT, and emphasize that prompt treatment can rapidly improve morbidity and prevent disease progression