© American Journal of Ethnomedicine Phytochemical Screening and In vivo Antiplasmodial Sensitivity Study of Locally Cultivated Artemisia annua Leaf Extract Against Plasmodium berghei

Objective of the study Medicinal plant research has become very important considering the herbal resources our rain forest is bestowed with which if harnessed could solve the challenges in malaria treatment in the area of accessibility and treatment cost. The present study on antimalarial activity of locally cultivated Artemisia annua in Langtang South area of Plateau State against Plasmodium berghei and the phytochemical screening of the leaf extract is to evaluate the efficacy, phytochemical content and possible indigenization of the herbal based medicine which for now is not native to Nigeria. Methodology In vivo anti-malarial sensitivity of plant extract was assessed using the 4-day test for anti-malarial activity against a chloroquine sensitive Plasmodium berghei NK65 strain in Swiss albino mice, Phytochemical analysis and the lethal dose (LD50) in mice screening were also determined