Key Words: Cost-effectiveness, Gestational diabetes, Screening

Objective: Early diagnosis of gestational diabetes mellitus (GDM) is important for both maternal and fetal health. The literature has vary-ing recommendations about one-step and two-step tests for GDM screening and diagnosis. The present study aimed to investigate the difference in the cost and duration of hospital stay of a one-step pro-cedure compared to a two-step procedure, which is routinely per-formed in our hospital. Materials and Methods: The two-step procedure was performed in 2,724 pregnant women, and the one-step procedure was performed in 185 pregnant women. The one-step and two-step screening pro-cedures for gestational diabetes were compared with respect to the duration of hospital stay and cost. Results: The test cost per woman was 0.75 TL less in the one-step procedure; however, the duration of the one-step test was 18.6 min longer, and the number of blood sampling procedures was 1.08 times higher. Conclusion: The one-step method may be preferred over the two-step (or glucose challenge) test due to its diagnostic value and lower cost