Fidelity Correction of Pressure Signals from Fluid-Filled Systems by Harmonic Analysis

Fluid-filled systems are generally used for invasive pressure measurements in cardiology, anesthesiology and intensive care medicine. Wave reflection and attenuation cause considerable signal distortion. The article presents the in vitro validation of a new commercially available device for the correction of distortion of pressures. Methods: The fluid-filled system consisted of different standard catheters, which were connected to the transducer using standard kits and alternatively lines of different length allowing a systematic variation of resonance frequency (6 Hz- 30 Hz). Enhanced damping was simulated by interposition of a damping device (R.O.S.E.) in the line. Correction data were calculated from a measurement of the transfer function. Pressure was generated by a pressure generator (Biotek) from tip-pressure signals collected from different patients fo