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Information technology in the logistics performance on road transport is expressed in terms of operation cost and turn round time. However, there are also many effects identified from the use of information technology in the road transport in perspective that are related to the relationships in the logistic performance. This study therefore seeks to fill this gap of knowledge by investigating the effect of Information technology on logistic performance on cargo transport in Kenya. The following variables are been tested; Information flow, Logistics integration, inventory management system and fleet management system. The study used descriptive research design. The target population is 105. The sample size will be 100 % of the target population. The study will use purposive sampling method because the study will get responses from particular group of respondents. The findings of the study indicated that there a significant influence of information technology on logistics performance. The study also found that the identified variables of information technology predict 90.9 % of logistics performance. The study recommends the cargo transportation companies should adopt information technology to improve the efficiency and effectiveness of their logistics performance in a bid to achieve a competitive advantage