www.ijcrcps.com Research Article IN-VITRO ANTIMICROBIAL ACTIVITY OF

The in-vitro antimicrobial evaluation on Tribulus terrestris confirms that, the plant appears to contain substances that exhibit measurable in vitro antimicrobial activity against some bacteria and fungi used in this study. The results of the various screening tests indicate that all the parts of this plant viz., leaves and stem possess some measurable inhibitory action against both gram-positive and gram-negative bacteria used in this study. However, the leaves of this plant alone possess significant inhibitory action against several bacteria as well as fungi than the other parts and therefore the leaves of this plant are endowed with antibacterial and antifungal properties. Among the various solvents used for the extraction and antimicrobial screening, the ethanol exhibited higher activity with regard to the inhibition of bacterial and fungal growth. It is screening to note that Pseudomonas aeruginosa, which is known to be a very resistant bacterium even to synthetic drugs, and Salmonella typhi, a multi drug resistant strain to Amphicillin and Chloramphenicol, which infects only human and produce typhoid fever were found to be very susceptible to the leaf extract of this plant I k-Fungal strains such as Aspergillus niger and Aspergillus flavus which usually parasitize man and animal and cause pulmonary Aspergillosis and Candida albicans an ubiquitous fungus associated with the pathogenesis of skin diseases, urinary tract infections, vulva vaginitis and oral thrash were also found to be susceptible to the Tribulus terrestri