Received on: 18-12-2014 Accepted on: 31-12-2014 Published on: 15-02-2015 Formulation and Evaluation of Rizatriptan

Oral disintegrating tablets have emerged as an alternative to the conventional oral dosage forms to improve the patient compliance. Due to problem in swallowing ability with age, the paediatric and geriatric patients complain of difficulty to take conventional solid dosage forms. The ODT’s are solid dosage forms that dissolve or disintegrate rapidly in the oral cavity. This results in solution or suspension without the need of water. The main objective of this work is to formulate and evaluate Rizatriptan Benzoate ODT’s using different concentration of super disintegrating agents like croscarmellose, Sodium Starch Glycolate (SSG), Crospovidone, Yellow potato starch. In this study uses different concentrations of diluents like Spry Dried Lactose, Avicel, Mannitol to optimize diluents concentration. After optimizing diluents concentration the study is continued by usin